INHIBITION OF PHOSPHODIESTERASE SUPPRESSES ALLERGIC LUNG INFLAMMATION BY REGULATING MCP-1 IN AN OVA-INDUCED ASTHMA MURINE MODEL WITH CO-EXPOSURE TO LIPOPOLYSACCHARIDE

Objective Asthma is a chronic inflammatory disease that can lead to severe problems with the respiratory system.This study aimed to evaluate the suppression of allergic airway inflammation of an asthma murine model by 3-isobutyl-1-methylxanthine (IBMX), which is a non-specific cyclic nucleotide phosphodiesterase (PDE) inhibitor.Methods Allergic lun

In extensive livestock production, high densities may inhibit regulation processes, maintaining high levels of intraspecific competition over time.During competition, individuals typically modify their behaviours, particularly feeding and bite rates, which can therefore be used as indicators of competition.Over eight consecutive seasons, we investi

The aim of this work is to show that a significant increase of the chorulon hcg efficiency of a Wave Energy Converter (WEC) can be achieved already at an early design stage, through the choice of a turbine and control regulation, by means of an accurate Wave-to-Wire (W2W) modeling that couples the hydrodynamic response calibrated in a wave flume to